How do adenosine A2A receptors regulate motor function?
نویسندگان
چکیده
منابع مشابه
Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling.
Dopamine, by activating dopamine D1-type receptors, and adenosine, by activating adenosine A(2A) receptors, stimulate phosphorylation of DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of M(r) 32,000) at Thr-34. In this study, we investigated the effect of metabotropic glutamate (mGlu) receptors on DARPP-32 phosphorylation at Thr-34 in neostriatal slices. A broad-spectrum mGlu receptor ag...
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2020
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2020.09.025